ethadione indications/contra

Stem definitionDrug idCAS RN
1072 520-77-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ethadione
  • aethadion
  • didione
  • dimedion
  • dimedione
  • ethadionum
  • petidion
  • Molecular weight: 157.17
  • Formula: C7H11NO3
  • CLOGP: 0.41
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 0
  • TPSA: 46.61
  • ALOGS: 0.01
  • ROTB: 1

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC N03AC03 NERVOUS SYSTEM
ANTIEPILEPTICS
ANTIEPILEPTICS
Oxazolidine derivatives

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Absence seizure indication 79631006 DOID:1825
Epilepsy indication 84757009 DOID:1826
Retinal disorder contraindication 29555009 DOID:5679
Proteinuria contraindication 29738008 DOID:576
Lymphadenopathy contraindication 30746006
Eaton-Lambert syndrome contraindication 56989000 DOID:0050214
Acute nephropathy contraindication 58574008
Hepatic failure contraindication 59927004
Disorder of optic nerve contraindication 77157004 DOID:1891
Leukopenia contraindication 84828003 DOID:615
Kidney disease contraindication 90708001 DOID:2527
Disease of liver contraindication 235856003 DOID:409
Lupus erythematosus and erythema multiforme-like syndrome contraindication 238926009
Pregnancy, function contraindication 289908002
Thrombocytopenic disorder contraindication 302215000 DOID:1588
Neutropenic disorder contraindication 303011007 DOID:1227
Porphyria contraindication 418470004 DOID:13268

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
CHEBI:81296 CHEBI
CHEMBL93047 ChEMBL_ID
C007637 MESH_SUPPLEMENTAL_RECORD_UI
I0F8O700BB UNII
10630 PUBCHEM_CID

Pharmaceutical products:

None